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rsv

RSV

Animal Models

  • BALB/c mice
  • African green monkeys

Study Types

  • Vaccine testing
  • Therapeutics testing
  • PK/safety testing

In vitro Services

  • Sample processing
  • QT-PCR viral load testing
  • Binding antibody ELISA

Representative Publication

 

Jones BG, Sealy RE, Rudraraju R, Traina-Dorge VL, Finneyfrock B, Cook A, Takimoto T, Portner A, Hurwitz JL. Sendai virus-based RSV vaccine protects African green monkeys from RSV infection. Vaccine. 2012 30:959-68.

Jerome Deval, Jin Hong, Guangyi Wang, Josh Taylor, Lucas K. Smith, Amy Fung, Sarah K. Stevens, Hong Liu, ZhinanJin, Natalia Dyatkina, MarijaPrhavc, Antitsa D. Stoycheva, Vladimir Serebryany, Jyanwei Liu, David B. Smith, Yuen Tam, Qingling Zhang, Martin L. Moore, Rachel Fearns, Sushmita M. Chanda, Lawrence M. Blatt, Julian A. Symons, and Leo Beigelman. Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate. PLoSPathog. 2015 Jun; 11(6): e1004995. PMCID: PMC4476725

Gabriela Ispas , Anil Koul, Johan Verbeeck, Jennifer Sheehan, Brigitte Sanders-Beer, Dirk Roymans, Koen Andries, Marie-Claude Rouan, Sandra De Jonghe, Jean-François Bonfanti, Marc Vanstockem, Kenneth Simmen, Rene Verloes. Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model. PLOSOne;  May 26, 2015 http://dx.doi.org/10.1371/journalpone.0126959